Regenerative Medicine · Mayfair, London
OzoneTherapy
10 – PASS · 20 – PASS · 30 – PASS · INSUFFLATIONS
Evidence-informed, clinically supervised Ozone Therapy at our Mayfair clinic, located at 58 South Molton Street.
Trained directly by Dr Johann Lahodny, the originator of multi-pass Ozone Therapy, our clinic offers 10-, 20- and 30-pass protocols alongside ozone insufflation options.
Your Ozone Therapy journey involves a consultation and suitability assessment before treatment. Your protocol will be personalised to your health history, goals and individual needs.
From £575 per session.
Regenerative Medicine
What is Ozone Therapy?
Ozone Therapy is a treatment that uses medical ozone (O₃), a reactive molecule made of three oxygen atoms. In blood-based treatment, a measured volume of blood is withdrawn, combined with a calibrated concentration of medical ozone and then returned to circulation.
Ozone Therapy is not simply about increasing oxygen levels. Exposure to medical ozone creates a brief oxidative signal designed to activate antioxidant and adaptive pathways. This biological response is the proposed mechanism through which treatment may support oxygen utilisation and cellular function.
Important to Know
Ozone is not inhaled during treatment. Specialised equipment keeps it contained within a controlled, closed system while the blood is treated and returned to circulation.
OZONE THERAPY, UV IV WITH OZONE & EBO₂
What are the Differences?
Each approach uses medical ozone but differs in how blood is treated, the volume processed and the additional technology involved.
Multi-pass Ozone Therapy
Blood is treated with medical ozone and returned in repeated cycles. At Nūūtro, the protocol may involve 10, 20 or 30 passes.
METHOD — Repeated treatment cycles
BLOOD PROCESSING — Measured batches
UV LIGHT — No
RELATIVE INTENSITY — Scales with pass count
FILTRATION — No
UV IV with Ozone
A limited volume of blood is drawn, exposed to selected ultraviolet wavelengths, combined with medical ozone and returned to circulation.
METHOD — UV Irradiation + Ozone
BLOOD PROCESSING — Limited draw
UV LIGHT — Yes
RELATIVE INTENSITY — Gentler than EBO₂
FILTRATION — No
EBO₂ THERAPY
Blood circulates continuously through an external medical-grade system for UV irradiation, specialised filtration, ozonation and photobiomodulation before being returned.
METHOD — Continuous extracorporeal circuit
BLOOD PROCESSING — 5–7 litres per session
UV LIGHT — Yes
RELATIVE INTENSITY — Most intensive
FILTRATION — Yes
Which approach is right for you?
There is no universally “best” option. The appropriate protocol depends on health history, clinical goals, treatment tolerance and clinical assessment.
Your Visit
The Nūūtro Experience
Your Ozone Therapy appointment is designed to feel calm, comfortable and cared for from the moment you arrive.
You will be guided through each stage, with time to settle in, ask questions and understand what to expect.
The focus throughout your visit is on creating a smooth and reassuring experience, allowing you to relax while every detail is taken care of.
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Clinical suitability assessment – Your health history and current medications reviewed by a registered nurse before treatment
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Private treatment rooms – Your session is yours alone, from arrival to aftercare
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Registered nurses – Present and attentive throughout every session
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Tailored protocols – Dosing, frequency, and combinations designed around you
Your Visit
Your Ozone Appointment
01. Before Your Appointment
Arrive well hydrated and eat a light meal beforehand unless advised otherwise.
Personalised preparation guidance will be provided before your visit.
02. During Your Session
Your registered nurse will monitor you throughout your session.
Appointment length ranges from 45 to 120 minutes depending on your selected protocol. Your registered nurse will confirm timings when you book.
03. After Your Session
Your registered nurse will provide personalised aftercare guidance.
You may resume your normal routine, while others may prefer to rest.
Preparation, suitability and aftercare recommendations are personalised according to your health history, clinical assessment and selected protocol.
The science
Oxygen at the Cellular Level
Around 90% of your body’s energy is generated through oxygen-dependent processes. When these become less efficient, through stress, inflammation, ageing or illness, energy production, immune function and tissue repair may all be affected.
Rather than simply delivering more oxygen, Ozone Therapy is intended to trigger adaptive biological responses. Medical ozone is understood to stimulate antioxidant pathways such as Nrf2, influence cytokine signalling and support cellular energy production through ATP-related mechanisms. Together, these responses may contribute to improved cellular resilience and systemic function.
Ozone’s antimicrobial properties are among the most extensively documented in the field, and underpin its long-standing use in sterilisation, water treatment and wound care. In clinical ozone practice, this same property is studied for its influence on microbial balance and immune signalling.
- ATP Production
- Cytokine Modulation
- NRF2 Pathway
- Stem Cell Research
- Antimicrobial Research
- 1800
in clinical use - 90%
Energy from Oxygen Processes - O3
Medical-grade Ozone
TARGETED OZONE THERAPY
Ozone Insufflations
Alongside our IV protocols, we offer targeted insufflation therapies that deliver medical-grade ozone locally rather than intravenously. These may be offered as standalone treatments or combined with an IV ozone session, subject to clinical assessment.
Rectal Insufflation
Medical-grade ozone is delivered rectally, one of the most widely used routes in ozone practice. Your registered nurse will recommend the most appropriate approach based on your health goals and initial assessment.
Vaginal Insufflation
Medical-grade ozone is delivered rectally, one of the most widely used routes in ozone practice. Your registered nurse will recommend the most appropriate approach based on your health goals and initial assessment.
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Combined insufflation (rectal & vaginal) — £220.
Available as a standalone appointment or alongside your IV ozone session.
How it works?
A Precise IV Protocol
Each cycle is called a “pass” that withdraws blood, ozonates it in a sterile closed loop system, and returns it to your bloodstream. We offer 10, 20, and 30-pass protocols, as well as the L1D 20-pass method. All sessions are delivered by registered nurses under clinical supervision.
STEP 01
Blood withdrawal
A small amount of blood is gently withdrawn from the patient into a sterile, sealed container. The process is similar to a standard blood draw, comfortable and quick.
Step 02
Ozonation
Medical grade ozone gas is infused into the blood inside the closed-loop system. The blood is carefully agitated to ensure full, even ozone exposure at the therapeutic dose.
Step 03
Reinfusion
The ozonated blood is returned to your bloodstream. This completes one pass. The cycle is then repeated according to your protocol — 10, 20, or 30 times.
L1D 20-Pass Ozone Therapy
CERTIFIED HIGH-DOSE PROTOCOL
A double-dose protocol developed by Dr Lahodny, delivering increased cumulative ozone exposure compared with standard multi-pass therapy. Suitability is assessed individually, and this protocol is not appropriate for every individual.
Treatment options
Choose your Protocol
The number of passes determines your cumulative ozone exposure. Our clinical team will recommend the most appropriate protocol based on your health history, goals, previous ozone experience and treatment tolerance. A higher number of passes does not automatically mean better results.
10 Pass
Ozone Therapy
£575 / session
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- Ideal introduction to Ozone Therapy
- Delivered using Dr Lahodny’s multi-pass protocol
- Our entry-level multi-pass protocol
- 45–60 minute session
- Registered nurse monitored
20 Pass — L1D Available
Ozone Therapy
£895 / session
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- Increased cumulative ozone exposureL1D upgrade available
- 60–90 minute session
- Registered nurse monitored
- Suitable as a step up from 10-pass
30 Pass
Ozone Therapy
£1,200 / session
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- Our highest cumulative ozone exposure
Suitable for experienced clients following assessment
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Our most comprehensive protocol
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90–120 minute session
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Nurse monitored throughout
Clinical authority
Trained by the Originator of High-Dose Ozone
Dr Johann Lahodny is the Austrian physician who developed high-dose Ozone Therapy, the protocol widely known as 10-pass. His work has focused on ozone’s proposed effects on mitochondrial function and stem cell activity, and it reshaped
how ozone is used in clinical practice internationally.
Our registered nurses have trained directly under Dr Lahodny and are certified in his protocols. We maintain contact with him and with other leading practitioners in the field to ensure our approach reflects current international practice.
- Training
Direct — Dr J. Lahodny - Protocol
L1D 20-Pass (certified) - Network
Global Ozone Leaders
Why ozone
Why Clients Choose Ozone
Cellular Energy
Ozone is thought to influence how efficiently cells use oxygen, supporting the metabolic processes behind stamina and physical performance.
Immune Resilience
Research explores ozone’s role in
modulating immune activity and the
body’s response to inflammatory stress.
Recovery & Repair
Studied for its proposed effects on
circulation and oxygen delivery, and the role these play in the body’s natural repair processes.
Mental Clarity
Clients often choose ozone when focus and mental sharpness feel harder to sustain. Research is exploring the links between cerebral oxygenation and cognitive performance.
Antioxidant Defence
Medical ozone creates a brief, controlled oxidative signal understood to stimulate the body’s own antioxidant pathways, including Nrf2.
Inflammatory Balance
Ozone’s proposed role in modulating inflammatory signalling is one of the most actively researched areas in the field.
Regenerative Signalling
Dr Lahodny’s high-dose protocols were developed around the hypothesis that ozone may influence stem cell mobilisation.
Mitochondrial Health
Mitochondrial function is central to cellular energy and resilience. A small peer-reviewed study co-authored by Dr Lahodny examined high-dose ozone’s effect on mitochondrial bioenergetics.
Is this for you?
Ozone Therapy Is For Many People
Ozone isn’t just for those managing chronic illness. It’s increasingly chosen by people who simply want to feel and perform at their best. We see a wide range of individuals across all stages of health.
- Chronic Fatigue & Brain Fog – For those feeling run-down, struggling to focus, or not recovering as quickly as they should.
- Post-Illness Recovery – Those who feel they haven’t fully bounced back after a period of illness, and are looking to support their recovery.
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Immune & Inflammatory Support – Those living with ongoing inflammatory or immune-related symptoms who want to support their overall resilience alongside their existing care.
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High-Demand Lifestyles – Executives, athletes, and busy parents who need to stay sharp, resilient, and consistently performing.
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Gut & Digestive Wellbeing – Individuals focused on digestive comfort and microbiome balance, often alongside a wider gut health programme.
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Longevity & Prevention – Individuals who feel well and want to stay that way, with a focus on energy, resilience and healthy ageing over the long term.
The evidence
Grounded in Science
Ozone Therapy has an extensive and growing body of peer-reviewed research behind it. Below are a selection of key studies that inform our clinical approach at Nūūtro.
01.
Ozone Therapy: A Critical Physiological and Diverse Clinical Evaluation
02.
Validity of Oxygen-Ozone Therapy as Integrated Medication Form in
Chronic Inflammatory Diseases
INGENTA CONNECT — CURRENT DRUG TARGETS
Please note:
We do not provide ozone therapies to treat any specific illness.
Our protocols are delivered as wellness and vitality therapy, and should not be interpreted as medical treatment for any named condition.
Your Questions Answered: Ozone Therapy FAQ
1. What is the difference between 10, 20, and 30-pass therapy?
The number of passes refers to how many times blood is withdrawn, ozonated, and returned. Higher-pass treatments deliver greater cumulative ozone exposure. A higher number of passes is not automatically more suitable, the right protocol depends on your individual assessment.
2. Does the treatment hurt?
Most people find the procedure comfortable. It is similar to a standard IV drip.
3. Are there any side effects?
Some clients experience temporary fatigue or flu-like symptoms shortly after treatment. This is usually short-lived. Less commonly, discomfort at the cannula site or light-headedness can occur. Your registered nurse will talk you through what to expect, and you’ll have access to our team throughout.
4. Can I Combine This With Other Therapies?
Ozone Therapy can be combined with IV nutrient therapy, EBO₂ and our other regenerative treatments. Our clinical team will discuss what’s appropriate for you during your consultation, based on your goals and suitability assessment.
5. Is IV ozone therapy safe?
Ozone Therapy is generally well tolerated when delivered under strict protocols by trained professionals. Suitability is assessed individually, some health histories and medications mean the therapy isn’t appropriate, which is why every client completes a suitability assessment before treatment.
6. How many sessions will I need?
Each treatment is tailored to your individual health goals, response, and needs. Our clinical team will guide the frequency and duration based on what’s most effective for you.
7. Will the Treatment Be Adjusted if Needed?
Yes. All protocols at Nūūtro are tailored to individual needs, and we regularly assess your response to adjust dosing, frequency, or combination with other therapies.
8. How Much Does Ozone Therapy Cost in London?
Pricing varies based on dosage: 10-pass therapy is £575 per session, 20-pass is £895 per session, and 30-pass is £1,200 per session. Insufflations (rectal and vaginal combination) are £220.
9. Can Ozone Help With Infections or Inflammation?
Ozone’s antimicrobial and anti-inflammatory properties are among the most extensively studied aspects of ozone science, and many clients choose ozone as part of a broader wellness strategy. We don’t treat medical conditions, and ozone therapy isn’t a substitute for medical care.
10. WHO ISN'T SUITABLE FOR OZONE THERAPY?
Ozone therapy isn’t appropriate for everyone. Pregnancy, certain blood disorders, and some medications mean the therapy may not be suitable. Every client completes a suitability assessment before treatment, and our clinical team will discuss any concerns with you.
CLIENT EXPERIENCES
Real Results, Real People
Individual experiences vary. Testimonials reflect personal experience and are not a guide to expected outcomes.
Feel the Difference Ozone Can Make
Speak with our team to find the right protocol for you.
Your journey begins with a consultation and suitability assessment, so we can make sure ozone therapy is appropriate for you.