Antimicrobial and Modulatory Effect
Ozone Therapy for HIV/SARS
In this article, we will break down the critical mechanisms in which ozone therapy can help in the conditions of :
- Human immunodeficiency virus (HIV), also called acquired deficiency syndrome (AIDS).
- Severe acute respiratory syndrome (SARS).
We will start by discussing both conditions as a description and their respective disease pathologies and then refer to ozone in the context of these conditions.
What is HIV?
The human immunodeficiency virus (HIV) is the virus that causes AIDS, a condition in which your body’s immune system is destroyed, and you are unable to fight off infections. HIV is transmitted through blood, semen, vaginal fluids, breast milk and other bodily fluids. It can be spread by sexual contact with an infected person, sharing needles, and from mother to child during pregnancy and childbirth. The most common symptoms of HIV infection are fever, fatigue and weight loss. Other symptoms may include cough, diarrhoea, night sweats and muscle aches.
The human immunodeficiency virus (HIV) is a disease that affects the immune system. It causes a gradual breakdown of the body’s ability to fight infections, leading to life-threatening illnesses like AIDS. HIV is a virus that causes the immune system to deteriorate and eventually fail. This means your body cannot fight off infections and become more susceptible to illnesses and diseases. HIV attacks your white blood cells and stops them from functioning correctly, leading to the gradual decline of your immune system. Eventually, this leads to Acquired Immunodeficiency Syndrome (AIDS), the most severe form of HIV infection.
HIV In More Detail
The human immunodeficiency virus (HIV) is a retrovirus. The virus attacks and destroys specific cells in your body called CD4 T lymphocytes, which are crucial to your immune system. As the virus destroys these cells, your body’s ability to fight off infections is weakened. CD4 cells are a type of white blood cell that play a significant role in protecting the body from infection. HIV uses the machinery of the CD4 cells to multiply and spread throughout the body.
What is SARS?
Severe acute respiratory syndrome, or SARS, is a type of respiratory infection that can be deadly if not treated correctly. The illness is caused by a coronavirus, a group of viruses that infects the upper airways and intestines.
SARS is a contagious disease that can be spread from person to person. It usually affects the upper respiratory tract but can also affect the lungs. SARS symptoms include fever, chills, a dry cough, shortness of breath, and body aches.
SARS can be life-threatening, especially if it causes pneumonia. The symptoms of SARS are similar to those of the flu, including fever, cough and shortness of breath.
Ozone Therapy and HIV/AIDS
Ozone has biological properties, among which the antimicrobial and modulatory effect on the immune system response is highlighted, which makes it possible to use in a complementary way to treat AIDS and HIV patients.
Mechanism of Action:
Unlike healthy human cells that love oxygen, primitive viruses – like HIV – which is found in AIDS and other diseases are lower life form viruses. These viruses and related bacteria are anaerobic. That means these microbes cannot live in oxygen. Therefore, when these anaerobic viruses are surrounded by a very energetic pure form of oxygen in the formation of medical-grade ozone, the viruses die off. If enough of this special form of oxygen/ozone were to be slowly and harmlessly introduced into the body every day for a few months, while bypassing the lungs and saturating every fluid and cell, the virus can no longer survive.
In 1900 Nikola Tesla operated the “Tesla Ozone Company” in the U.S. Between 1958 and 1973, Dr. Robert Mayer and Dr. Edmund J. Ryan were granted 8 U.S. ozone patents, and European physicians have reported successfully using ozone for over 50 years to cure 33 major diseases. Ozone therapy is not a new concept and has been around for a long time. So, let’s discuss the use of ozone-treated blood in the therapy of HIV infection and immune disease!
In one study:
- No significant toxicity was observed in a phase 1 study based on ten patients.
- Additionally, three patients with moderate immunodeficiency showed improved surrogate markers of HIV-associated immune disease.
Carpendale et al., conducted a study reporting the analysis that “ozone inactivated HIV at noncytotoxic concentrations”. Furthermore, this study showed that complete inactivation of HIV suspensions was achieved by ozone therapy. It was also reported that the HIV p24 core protein was reduced in all ozone-treated cultures compared to control cultures, with an average reduction of 46%. An article in the Journal of Ozone Therapy by Cespedes-Suarez analyzed the immune response behaviour in HIV-AIDS patients treated with ozone therapy for two years.
- Ozone was administered systemically via the blood.
- Thirty-two patients were involved.
- Protocol of 15 sessions and maintenance every 15 days.
- The initial dose was 4000 µg/ml to 12,000 µg/ml.
- The maintenance dose was 50 µg/ml.
- The team indicated viral load, CD4 and CD8 count before and at the end of therapy.
- The results showed a significant decrease in viral load to undetectable values and an increase of CD4 and CD8 at the end of the 15 sessions, being maintained at 2 years of treatment, thus achieving a permanent activation of the immune system and improving the quality of life of these patients.
In 1990, using special ozone equipment, HIV-infected blood was converted from HIV+ to HIV- in less than 16 seconds, in vitro, by inventor Basil Wainwright. A Mr. James Pauls, Snr., (HIV+) was treated, and in only eight treatments, a 220% improvement in his T/4 cell response was achieved. The October 1st issue of the Journal of the American Society of Haematology published the ozone\HIV work of the medical doctors’ Wells, Latino, Galvachin, & Poiesz.
Their work titled Inactivation Of HIV Type 1 by Ozone In Vitro describes the research by oncologist Dr Bernard Poiesz from the Syracuse State University of New York Research Hospital. The group performed 15 replications of an ozone study that interfaced ozone with HIV-infected factor 8 blood. The ozone completely removed the HIV from the blood 97 to 100% of the time, yet was non-toxic to standard healthy blood components.
If ozone has hereby been proven in a peer-reviewed journal to work so safely and effectively, registering a 97 -100% kill rate on the most virulent recombinant virus known to man, that being HIV, how much more effective is it in the treatment of ALL the other lesser viruses?
Ozone Therapy and SARS
Ozone therapy seems to have an immunological role on SARS, and even COVID-19, because of the modulation of cytokines and interferons, including the induction of gamma interferon. The data suggests the possible role of ozone therapy in SARS, either as a monotherapy or, more realistically, as an adjunct to standard treatment regimens. Furthermore, due to the recent COVID-19 outbreak, there has been an increasing interest in the role of ozone therapy for SARS.
Mechanism of Action:
Ozone exerts antiviral activity by inhibiting viral replication and direct inactivation of viruses. Additionally, ozone can act as an antiviral drug enhancer, furthering the efficacy of combined treatment. Following this point, studies have shown that combined ozone and antiviral treatment reduced inflammation and lung damage.
Systemic ozone therapy seems helpful in controlling inflammation, stimulating immunity and has antiviral activity. Likewise, ozone protects acute coronary syndromes and ischaemia reperfusion damage, thus suggesting a new methodology of immune therapy. Compounding ozone’s use as a complimentary adjuvant to antiviral drugs, ozone has also been proven useful in helping to increase host immunity against infection.
Ozone has been shown to activate cellular and humoural immune systems, and can reduce inflammatory and apoptotic processes. Several data describe the role of ozone in treating hypoxia within the body by improving oxygen saturation and increasing oxygen supply. It is imperative to note that the efficacy of ozone therapy is shown in the early stage of viral disease, i.e. before invasive ventilation is necessary. Furthermore, ozone therapy is very inexpensive and safe, and resistance is not developed, so can be safely exploited in many SARS viruses.
In addition, ozone stimulates the red blood cell glycolysis rate, leading to an increased amount of oxygen released to the tissues and the Krebs cycle, resulting in an increased production of ATP. Ozone also significantly reduces NADH concentration and helps oxidize cytochrome C, thus stimulating oxygen metabolism, and shows anti-inflammatory and possible cytoprotective action interacting with NF-KB and Nrf2 transcription agents.
Through the oxidation of double bonds, ozone possesses the unique ability to inactivate biological contaminants, including viruses. Ozone disrupts the integrity of the bacterial cell walls causing their lysis and death, and can effectively control spore germination of various dermatophytes.
Murray and coworkers demonstrated the efficacy of ozone a few years ago against a variety of simple and complex viruses, including enveloped, non-enveloped, DNA, and RNA ones. Ozone is triatomic oxygen (O3), the most powerful oxidant found in nature. Ozone therapy improves:
- Blood rheology.
- Oxygen delivery.
- Oxygen utilization.
- Endothelial nitric oxide production.
- Immune modulation via cytokine induction.
The mechanism of ozone is the perfect match for viral vulnerability. The cysteine-rich structures within viruses are highly vulnerable to oxidation via ozone, which will effectively cripple its biochemical activity in the viral proteins. Thus, the viral enzymes become inactive when reduced and oxidized. Viruses, unlike “living” cells, have no mechanism of self-repair.
Life Quality Improvement
A Viable Solution
If you live in London and are interested in ozone therapy for any form of acute and chronic condition, please reach out to a member of our team. Ozone therapy is a viable solution for managing AIDS, HIV and SARS.
So if you, or anyone you love, has been diagnosed with one of these conditions and are looking for a way to improve the quality of your life, Nüütro is here for you. The truth is that when you’re dealing with one of these conditions, it can feel like there’s no hope. But there is hope! There are ways to manage and even beat them. And you won’t find that hope anywhere else but Nūūtro Health and Wellness.
We know how important it is to have someone who understands where you’re coming from and knows how to provide solutions that make sense for your life. That’s why we take the time to get to know each individual who walks through our doors—and why we do everything we can to help them find solutions that work for them.
We don’t believe that disease should define you or what you do, nor should your treatment method.
Garber, G.E. et al., 1991. The use of ozone-treated blood in the therapy of HIV infection and Immune Disease. AIDS, 5(8), pp.981–984.
Cespedes-Suarez, J. et al., 2018. The immune response behavior in HIV-AIDS patients treated with ozone therapy for two years. Journal of Ozone Therapy, 2(3).
Carpendale, M.T.F. & Freeberg, J.K., 1991. Ozone inactivates HIV at noncytotoxic concentrations. Antiviral Research, 16(3), pp.281–292.
Cattel, F. et al., 2021. Ozone therapy in COVID-19: A narrative review. Virus Research, 291, p.198207.
Khan, S.A. et al., 2017. Ozone therapy: An overview of pharmacodynamics, current research, and clinical utility. Medical Gas Research, 7(3), p.212.
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Galiè, M. et al., 2018. Mild ozonisation activates antioxidant cell response by the KEAP1/nrf2 dependent pathway. Free Radical Biology and Medicine, 124, pp.114–121.
Gavazza, A. et al., 2020. Ozone therapy as a possible option in COVID-19 Management. Frontiers in Public Health, 8.
Murray, B.K. et al., 2008. Virion disruption by ozone-mediated reactive oxygen species. Journal of Virological Methods, 153(1), pp.74–77.
Robert Jay, R. & Howard, R., 2020. A plausible “penny” costing effective treatment for Corona virus – ozone therapy. Journal of Infectious Diseases and Epidemiology, 6(2).